"MITT & Intracellular Protein Therapy"

  • CV-01

    Establishment of MITT enabled by the latest form of hydrophobic CPPs – advanced MTDs to deliver biologically active macromolecules

  • CV-02

    Improvement of CP-SOCS3 As Anti-Cancer Agent Against Various Cancer & Its Optimization As Therapeutic Candidate for Preclinical Development

  • CV-03

    Development of Protein-Based Anti-Cancer Agent with Gastrointestinal Track (GIT)-Specific Tumor Suppressor GPX7 & Determination of Its Therapeutic Applicability

  • CV-04

    Anti-GIT Cancer Agent: Cell-Permeable TFF1 Fused to Advanced MTD/SD & Its Application for Treatment of Various GIT Cancer

  • CV-05

    Development of TGF-β Signaling-Specific Anti-Cancer Agent: iCP-CV-05 to Illustrate the Use of Protein-Based Therapy to Target Solid Cancer

  • CV-06

    Improvement of Cell-Permeable CV-06 by Adopting aMTD/SD fusion to Suppress Parkinson Disease-Associated Phenotypes

  • CV-07

    Establishment of Deep Tissue Delivery of CV-07-01 and CV-07-02 with aMTD-Enabled MITT for Osteogenesis and Bone Healing Therapy

  • CV-08

    Establishment of Protein-Based Obesity Therapy by Inhibiting the Interaction of ObR & SOCS3 with Cell-Permeable CV-08-01 and/or CV-08-02

  • CV-09

    Commercialization of CV-09 As A Research Reagent for Development of Epigenetic Animal Model

  • CV-10

    Commercialization of CV-10 as A Research Reagent for Generation of iPS Cells & Stem Cell Therapy

  • CV-11

    Commercialization of CV-11 as a Research Reagent for Genome/Gene Editing Nuclease

  • CV-12

    Commercialization of CV-12 as a Research Reagent for Direct Conversion from Somatic Cells to Desired Cells

Research Overview

The plasma membrane normally acts as an impermeable barrier, preventing proteins and other macromolecules from entering cells. However, Cellivery’s proprietary MITT allows functionally active macromolecules to rapidly transverse cellular membranes.

Platform Technology

Protein transduction exploits the ability of specific basic-, amphipathic- and hydrophobic- cell penetrating peptide (CPP) sequences to enhance the uptake of proteins and other macromolecules by mammalian cells.